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1,2,4-Triazole is a planar molecule. The C-N and N-N distances fall into a narrow range 136 - 132 picometers, consistent with the aromaticity. [ 2 ] Although two tautomers can be envisioned, only one exists practically speaking. 1,2,4-Triazole is amphoteric, being susceptible to both N-protonation and deprotonation in aqueous solution.
Triazole. A triazole is a heterocyclic compound featuring a five-membered ring of two carbon atoms and three nitrogen atoms with molecular formula C 2 H 3 N 3. Triazoles exhibit substantial isomerism, depending on the positioning of the nitrogen atoms within the ring. Many triazoles are versatile, biologically active compounds commonly used as ...
3-Amino-1,2,4-triazole ( 3-AT) is a heterocyclic organic compound that consists of 1,2,4-triazole with an amino group as a substituent . 3-AT is a competitive inhibitor of the product of the HIS3 gene, imidazoleglycerol-phosphate dehydratase. [ 3][ 4] Imidazoleglycerol-phosphate dehydratase is an enzyme catalyzing the sixth step of histidine ...
1,2,3-Triazole is one of a pair of isomeric chemical compounds with molecular formula C 2 H 3 N 3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms. 1,2,3-Triazole is a basic aromatic heterocycle.
The Einhorn–Brunner reaction is the designation for the chemical reaction of imides with alkyl hydrazines to form an isomeric mixture of 1,2,4-triazoles. It was initially described by the German chemist Alfred Einhorn in a paper, published in 1905, describing N-methylol compounds of amides. [1] In 1914 chemist Karl Brunner published a paper ...
Estazolam, sold under the brand name Prosom among others, is a tranquilizer medication of the triazolobenzodiazepine (TBZD) class, which are benzodiazepines (BZDs) fused with a triazole ring. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Estazolam is an intermediate-acting oral ...
Infobox references. 4-Phenyl-1,2,4-triazoline-3,5-dione (PTAD) is an azodicarbonyl compound. PTAD is one of the strongest dienophiles and reacts rapidly with dienes in Diels-Alder reactions. [1] The most prominent use of PTAD was the first synthesis of prismane in 1973. [2]
Prothioconazole is a synthetic chemical produced primarily for its fungicidal properties. It is a member of the class of compounds triazoles, and possesses a unique toxophore in this class of fungicides. Its effective fungicidal properties can be attributed to its ability to inhibit CYP51A1.